The study developed a cancer-based and a non-cancer based toxicity value and compared those values to appropriate estimates of human exposure to TBBPA. The data collectively indicated a low level of health concern associated with exposures to TBBPA based on current data.1Source: Wikoff, Daniele, Chad Thompson, Camarie Perry, Matthew White, Susan Borghoff, Lauren Fitzgerald, and Laurie C. Haws. “Development of toxicity values and exposure estimates for tetrabromobisphenol A: application in a margin of exposure assessment.” Journal of Applied Toxicology 35, no. 11 (2015): 1292-1308.
Key Takeaways:
- The evaluation found margin of exposure (MOE) estimates of 32,000,000 and 800,000.
- MOE demonstrates that even when maximum concentrations of TBBPA in the diet, breast milk, soil/dust and water were used the resulting exposures were many orders of magnitude below any reported adverse effects seen in research animal studies.
